Is this what you are referring to?
View attachment 310097
Is this Grade A/B/C a setting, a threshold, different models of this ADC? What does that mean? Sorry I'm not an analogy guy.
It's sort of like a CPU. They all use the same ESS ADC chip, but some are better than others. The E1DA Cosmos ISO has isolated power (but then you need two cables) as opposed to being bus powered.

Getting grade B means you "only" measure to 126-127dB SNR as opposed to 128-129. Grade B is plenty and what @VintageFlanker uses, I believe.