One more huge variable is the type, and diameter, of the ear tip. I find the Zero2 to be one of the most difficult to fit IEMs because they have one of the shortest nozzles in my collection, and I've heard other people have this same issue (I'm aware that for some people the short nozzle works better with their ear shape). This caused me to try many, many, different ear tips. I did finally find some that worked for me (AZLA Origin, with their long stem), but in the process I tried a few tips that have wider bores, and in general, I find that wide bore tips seem to accentuate higher frequencies. I recall that I did manage to get a seal with one set of wide bore tips, and the treble was almost piercing with those, and I don't have that problem with the AZLAs that don't have as wide an opening. In fact, the Truthear RED comes with two different sets of tips, one with narrow bore, and one with wide, and they have very different tonalities, at least to my ears. So, given how much of an impact just the bore diameter of the ear tips makes, I'm sure different ear anatomies and insertion depth must also make a massive difference in how people hear their IEMs.