I've followed ASR for awhile without posting anything, but just saw this thread and wanted to chime in. There's actually a pair of Bliesma M74s making their way to me through customs right now.
Anyway, some comments for you,
@thin bLue :
1) The only reason you'd want to use the T34 tweeter is if you were going passive and wanted to match the 97db sensitivity of the dome. But with a 3" dome, you really are going to want to cross higher rather than lower, so you'd be better off with the smaller T25. If you're going active, the sensitivity mismatch won't matter, and a smaller tweeter lets you get the center-to-center spacing closer.
2) You can use the M74 down to 600hz or so with a steep crossover, so you need a hand-off here to a woofer that can play cleanly up to that same level. This means you can't really use anything larger than a 10" without having to worry about weird issues in the crossover range. I think the 8" Purifi that you've chosen would probably be great here. I built a Purifi-based 4-way as my pandemic project, and those Purifi's are *amazing*. (I really, really want them to come out with a 10".)
3) That W38 is an odd bird. I really want to like it, but every time I look at it, I get mad at scan speak. Too expensive, and it rolls off way too high. When I've modeled it, I always end up having to pair it with a subwoofer. So although it's bigger than the 8" Purifi, they both are going to roll off right around the same place. But the 15" can't play as high, so you aren't going to be able to get it up to where the M74 needs to hand off. So in that case, you sort of have to ask yourself if you'd be better off just going 3-way with the 8" (or multiple 8's?). The Bliesmas are both sealed, so you don't need separate chambers for them, so your entire box size would be based on the Purifi.
4) If you drop the 38we, and still want to do a 4-way, then I'd either just add a couple 8" purifis, or look into adding a subwoofer. I used a 13" Scanspeak sub in my Purifi build for the lowest couple of octaves, and unlike the 38we, those can go really low. If you go sealed with a little boost, the sub is only going to need 1-1.5 cubic feet, so it won't make your tower too gigantic.
Hope that helps. Please post some pics if you get started on the project.
Thx,
E