The majority of floorstanding loudspeakers will still need an additional sub/s if you want really full-range.
If we start with that assumption ("subs are needed if we want really fullrange"), then the additional enclosure size of a floorstanding format can be applied towards improved performance in the rest of the spectrum. The net result would arguably avoid the inefficiency of having the main speakers duplicate some (if not most) of what the subs are going to be doing anyway. Offhand I don't think this is something very many manufacturers do, but this weekend a manufacturer I did some work for will be showing big main speakers designed from the outset with the assumption that subs would be used.