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[No Politics] What you need to know about CoVID-19 by SARS-CoV-2 [No Politics]
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maty
Major Contributor
If people think masks don’t work or are detrimental to their own health, would face shields be an option that would satisfy in both sides of the spectrum?
I have an adult niece that read an article from a nurse with a Master’s degree that more or less stated that healthy people shouldn’t wear masks and they actually knock down the wearer’s immunity.
There was a heated argument at a family gathering and I refused to participate since it was just going in circles.
I have an adult niece that read an article from a nurse with a Master’s degree that more or less stated that healthy people shouldn’t wear masks and they actually knock down the wearer’s immunity.
There was a heated argument at a family gathering and I refused to participate since it was just going in circles.
Switzerland may be open internally but is still isolating per this:
"Switzerland
Switzerland, who brought in border controls on March 13, will reopen its frontiers with Germany, Austria and France on June 15 if the situation allows.
All travel restrictions at the border with Italy will remain in place until further notice.
Any foreign nationals who wish to enter Switzerland and do not hold a valid residence or work permit will be refused entry."
https://www.euronews.com/2020/05/27...ir-borders-ahead-of-the-summer-holiday-season
---
I don't know of any travel blockades within the United States...
Will have to check the status of border crossings, though. --- restrictions on cross-border travel extended to June 20
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maty
Major Contributor
These and other topics are not worth discussing. Everyone believes that their opinion is as valid as any other regardless of their academic background and, above all, the amount of data and statistics that one provides.
The contempt for facts, data and mathematics is overwhelming, at least in Spain. Everything is opinion and opinion, in a discussion they only seek to win it and not in finding the truth.
That is why science and, above all, scientific thought are so mistreated in Spain, due to their low appreciation.
Police have just closed one of the big meat processing plants in the Netherlands because of unsafe work/transportation practices. It also looks as if in this plant the subcontractors had brought in some of the workers from another plant of the same company that had been closed earlier because 20% of its workforce had been infected.
maty
Major Contributor
La Sociedad Española de Medicina Interna (SEMI) publica los resultados preliminares del primer gran registro clínico nacional multicéntrico sobre COVID-19 que contiene datos ya de 12.200 pacientes y en el que participan 600 investigadores de casi 150 hospitales
[Spanish] https://www.fesemi.org/informacion/...a-interna-publica-los-resultados-preliminares
The Spanish Society of Internal Medicine (SEMI) publishes the preliminary results of the first large national multicenter clinical registry on COVID-19 that contains data from 12,200 patients and in which 600 researchers from almost 150 hospitals participate
https://translate.google.es/translate?sl=es&tl=en&u=https://www.fesemi.org/informacion/prensa/semi/la-sociedad-espanola-de-medicina-interna-publica-los-resultados-preliminares
[ Mortality from SARS-CoV-2 was similar to that observed in some data series from China and the USA. But it was higher than that described in Italy and lower than the figure observed in the United Kingdom. The demographic factors such as age or comorbidities, may explain in part the differences in mortality SARS-CoV-2, among other factors related to pressure situation the health system. In Italy, the greatest burden of disease was limited to the Lombardy region, while in Spain "it has been more widely distributed." However, most of the patients in the SEMI study are from Madrid, one of the regions most affected by COVID-19.and where the situation is comparable to that of northern Italy. This will be explored in other studies already in progress.
The 31.5% of the Spanish patients, according to these first preliminary results, developed breathlessness and mortality was the 21.1%, with a marked increase in function of age. At older age, higher mortality was found. In the 80-89 year span, for example, it reaches 42.5% ... ]
-> Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.
https://www.medrxiv.org/content/10.1101/2020.05.24.20111971v1
[ ...The most frequent symptoms were fever (86.2%) and cough (76.5%).
High values of ferritin (72.4%), lactate dehydrogenase (70.2%), and D-dimer (61.5%), as well as lymphopenia (52.6%), were frequent.
The most used antiviral drugs were hydroxychloroquine (85.7%) and lopinavir/ritonavir (62.4%).
31.5% developed respiratory distress. Overall mortality rate was 21.1%, with a marked increase with age (50-59 years: 4.2%, 60-69 years: 9.1%, 70-79 years: 21.4%, 80-89 years: 42.5%, ≥ 90 years: 51.1%).
Conclusions. The SEMI-COVID-19 Network provides data on the clinical characteristics of patients with COVID-19 hospitalized in Spain. Patients with COVID-19 hospitalized in Spain are mostly severe cases, as one in three patients developed respiratory distress and one in five patients died. These findings confirm a close relationship between advanced age and mortality. ]
[Spanish] https://www.fesemi.org/informacion/...a-interna-publica-los-resultados-preliminares
The Spanish Society of Internal Medicine (SEMI) publishes the preliminary results of the first large national multicenter clinical registry on COVID-19 that contains data from 12,200 patients and in which 600 researchers from almost 150 hospitals participate
https://translate.google.es/translate?sl=es&tl=en&u=https://www.fesemi.org/informacion/prensa/semi/la-sociedad-espanola-de-medicina-interna-publica-los-resultados-preliminares
[ Mortality from SARS-CoV-2 was similar to that observed in some data series from China and the USA. But it was higher than that described in Italy and lower than the figure observed in the United Kingdom. The demographic factors such as age or comorbidities, may explain in part the differences in mortality SARS-CoV-2, among other factors related to pressure situation the health system. In Italy, the greatest burden of disease was limited to the Lombardy region, while in Spain "it has been more widely distributed." However, most of the patients in the SEMI study are from Madrid, one of the regions most affected by COVID-19.and where the situation is comparable to that of northern Italy. This will be explored in other studies already in progress.
The 31.5% of the Spanish patients, according to these first preliminary results, developed breathlessness and mortality was the 21.1%, with a marked increase in function of age. At older age, higher mortality was found. In the 80-89 year span, for example, it reaches 42.5% ... ]
-> Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.
https://www.medrxiv.org/content/10.1101/2020.05.24.20111971v1
[ ...The most frequent symptoms were fever (86.2%) and cough (76.5%).
High values of ferritin (72.4%), lactate dehydrogenase (70.2%), and D-dimer (61.5%), as well as lymphopenia (52.6%), were frequent.
The most used antiviral drugs were hydroxychloroquine (85.7%) and lopinavir/ritonavir (62.4%).
31.5% developed respiratory distress. Overall mortality rate was 21.1%, with a marked increase with age (50-59 years: 4.2%, 60-69 years: 9.1%, 70-79 years: 21.4%, 80-89 years: 42.5%, ≥ 90 years: 51.1%).
Conclusions. The SEMI-COVID-19 Network provides data on the clinical characteristics of patients with COVID-19 hospitalized in Spain. Patients with COVID-19 hospitalized in Spain are mostly severe cases, as one in three patients developed respiratory distress and one in five patients died. These findings confirm a close relationship between advanced age and mortality. ]
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No, it's not more testing, but there are more positive tests.
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Nurses provide nursing care; they are not filtration experts or virologists. Worse, oral meme transmission is suspect. Stick to expert recommendations or if you have sufficient background in the ara, read journal articles yourself and Read the Methods section FIRST.
[1] Wrong. Even healthy people should wear masks to protect themselves and to protect others. This assertion is likely based on the early advice to save masks, or the better, N95 masks, for use by medical workers - including of course nurses.
[2] Negligible. Living a sufficiently sheltered existence (say 24/7 in a semi-cond. fab) can - over time - degrade immune system function by preventing low level challenges to the immune system. BUT that would take a while AND is a nullity compared to the risks of going w/o any mask.
maty
Major Contributor
Italia [Lombardía] registra un repunte en el número de fallecidos y de nuevos contagios
[Spanish] https://www.elperiodico.com/es/soci...repunte-muertos-contagios-coronavirus-7977651
Italy [Lombardy] registers a rebound in the number of deaths and new infections
https://translate.google.es/transla...repunte-muertos-contagios-coronavirus-7977651
[ As reported by Civil Protection, in the last 24 hours there have been another 117 deaths, a figure that contrasts with the 78 registered on Tuesday, while 584 other cases have been added, compared to 397 the day before. In total, there are already 231,139 confirmed cases and 33,072 deaths from the pandemic.
65% of the new cases have occurred in Lombardy, the region that has suffered the most and which, to date, total 87,800 cases and almost 16,000 deaths. In the last day alone, the northern region has recorded another 58 deaths and 384 new infections.
On the other hand, the number of cured patients continues to increase at a similar rate as in previous days, with another 2,443 people who have been discharged and a total of 147,101 cured.
Currently, there are only 505 patients admitted to the ICU, 16 fewer than on Tuesday, while hospitalized patients have fallen to 7,729, 188 fewer. 84 percent of the active cases in the country are in asymptomatic home isolation or with mild symptoms... ]
[Spanish] https://www.elperiodico.com/es/soci...repunte-muertos-contagios-coronavirus-7977651
Italy [Lombardy] registers a rebound in the number of deaths and new infections
https://translate.google.es/transla...repunte-muertos-contagios-coronavirus-7977651
[ As reported by Civil Protection, in the last 24 hours there have been another 117 deaths, a figure that contrasts with the 78 registered on Tuesday, while 584 other cases have been added, compared to 397 the day before. In total, there are already 231,139 confirmed cases and 33,072 deaths from the pandemic.
65% of the new cases have occurred in Lombardy, the region that has suffered the most and which, to date, total 87,800 cases and almost 16,000 deaths. In the last day alone, the northern region has recorded another 58 deaths and 384 new infections.
On the other hand, the number of cured patients continues to increase at a similar rate as in previous days, with another 2,443 people who have been discharged and a total of 147,101 cured.
Currently, there are only 505 patients admitted to the ICU, 16 fewer than on Tuesday, while hospitalized patients have fallen to 7,729, 188 fewer. 84 percent of the active cases in the country are in asymptomatic home isolation or with mild symptoms... ]
maty
Major Contributor
maty
Major Contributor
CDC Says Possibly 'Less Than Half' Of Positive Antibody Tests Are Correct
https://www.forbes.com/sites/tommyb...-half-of-positive-antibody-tests-are-correct/
[ However, the CDC has acknowledged that antibody testing can frequently be inaccurate, especially in populations where there is a low prevalence of the coronavirus.
In fact, under certain scenarios, “less than half of those testing positive will truly have antibodies,” the agency says.
This is particularly dangerous because it could lead to individuals believing they have been infected with the coronavirus, and acting as if they have immunity, when that is not the case.
As a result, the CDC advises that antibody test results should not be used to make decisions related to schools, dormitories, or correctional facilities, and that testing shouldn't be used to determine immune status in individuals... ]
https://www.forbes.com/sites/tommyb...-half-of-positive-antibody-tests-are-correct/
[ However, the CDC has acknowledged that antibody testing can frequently be inaccurate, especially in populations where there is a low prevalence of the coronavirus.
In fact, under certain scenarios, “less than half of those testing positive will truly have antibodies,” the agency says.
This is particularly dangerous because it could lead to individuals believing they have been infected with the coronavirus, and acting as if they have immunity, when that is not the case.
As a result, the CDC advises that antibody test results should not be used to make decisions related to schools, dormitories, or correctional facilities, and that testing shouldn't be used to determine immune status in individuals... ]
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ernestcarl
Major Contributor
Hmmmn... I would like to go through this thread, but there's now over 100 pages!
Here's a weekly series that covers and reviews the relevant scientific literature: MGH Division of Infectious Diseases
Part 6 has been released a few hours ago.
And attached is a printout summary of parts 1-4 for anyone interested. If you've got the time and patience, good luck reading/watching the whole series!
Here's a weekly series that covers and reviews the relevant scientific literature: MGH Division of Infectious Diseases
Part 6 has been released a few hours ago.
And attached is a printout summary of parts 1-4 for anyone interested. If you've got the time and patience, good luck reading/watching the whole series!
maty
Major Contributor
Sanidad se inclina por mantener el uso de hidroxicloroquina en pacientes con coronavirus
[Spanish] https://www.rtve.es/noticias/202005...droxicloroquina-frente-covid-19/2015034.shtml
Health [Spain] is inclined to maintain the use of hydroxychloroquine in patients with coronavirus
https://translate.google.es/translate?sl=es&tl=en&u=https://www.rtve.es/noticias/20200527/sanidad-se-inclina-mantener-uso-hidroxicloroquina-frente-covid-19/2015034.shtml
[ The Ministry of Health is currently maintaining the use of hydroxychloroquine in COVID-19 patients and in clinical trials against the disease. It also recommends not stopping treatment of chronic patients with other diseases despite the fact that the World Health Organization has temporarily suspended clinical trials with this drug.
The WHO decided to stop its trial after the publication of a study in the medical journal The Lancet, which indicated higher mortality rates in COVID-19 patients and an increase in cardiac arrhythmias in which treatments with hydroxychloroquine, a drug, had been used. commonly used to treat malaria, lupus, or rheumatoid arthritis.
In a statement sent to RTVE.es, the Spanish Agency for Medicines and Health Products, under the Ministry of Health, rules out suspending treatment with the drug, although it will continue to monitor carefully the effects it may cause. On the WHO's decision, he recalls that the trial used "higher doses than in other studies." "We have not received any warning signs from any of the studies that are being carried out in the national territory," says the agency, which stresses that both chloroquine and hydroxychloroquine "have a well-known efficacy and safety profile." ]
[Spanish] https://www.rtve.es/noticias/202005...droxicloroquina-frente-covid-19/2015034.shtml
Health [Spain] is inclined to maintain the use of hydroxychloroquine in patients with coronavirus
https://translate.google.es/translate?sl=es&tl=en&u=https://www.rtve.es/noticias/20200527/sanidad-se-inclina-mantener-uso-hidroxicloroquina-frente-covid-19/2015034.shtml
[ The Ministry of Health is currently maintaining the use of hydroxychloroquine in COVID-19 patients and in clinical trials against the disease. It also recommends not stopping treatment of chronic patients with other diseases despite the fact that the World Health Organization has temporarily suspended clinical trials with this drug.
The WHO decided to stop its trial after the publication of a study in the medical journal The Lancet, which indicated higher mortality rates in COVID-19 patients and an increase in cardiac arrhythmias in which treatments with hydroxychloroquine, a drug, had been used. commonly used to treat malaria, lupus, or rheumatoid arthritis.
In a statement sent to RTVE.es, the Spanish Agency for Medicines and Health Products, under the Ministry of Health, rules out suspending treatment with the drug, although it will continue to monitor carefully the effects it may cause. On the WHO's decision, he recalls that the trial used "higher doses than in other studies." "We have not received any warning signs from any of the studies that are being carried out in the national territory," says the agency, which stresses that both chloroquine and hydroxychloroquine "have a well-known efficacy and safety profile." ]
maty
Major Contributor
The graph is beyond me but maybe it is useful for some.
maty
Major Contributor
Contagios diarios en 4 empresas cárnicas: ¿qué está ocurriendo en el brote de Lleida [Cataluña, España]?
[Spanish] https://www.elconfidencial.com/tecn...navirus-cataluna-generalitat-covid19_2612600/
Daily infections in 4 meat companies: what is happening in the Lleida [Catalonia, Spain] outbreak?
https://translate.google.es/translate?sl=es&tl=en&u=https://www.elconfidencial.com/tecnologia/ciencia/2020-05-27/lleida-coronavirus-cataluna-generalitat-covid19_2612600/
[ Lleida went from having a cumulative incidence rate in the last seven days from 12.1 cases per 100,000 inhabitants to 42.7 cases on May 22. For a province of just 430,000 inhabitants, the data is a serious wake-up call...
The Health Department of the Generalitat recognized this week that the reason for the rebound is due to four fronts: new cases in residences, in health personnel, in slaughterhouses and at a birthday party with 20 people. However, the most unexpected is that produced in various meat companies in the province. "There are a total of four companies, but I prefer not to give their names. We are seeing a daily drip of infections from workers of these companies, about 3-4 cases a day. And also from their families. The rest of the cases are normal. No we are seeing more incidence in nursing homes or health personnel than expected compared to other Autonomous Communities," explains a health source familiar with the situation in Lleida who asks for anonymity...
This same source indicates that the problem of positives in meat companies has a double aspect. On the one hand, they are jobs with a high risk of contagion due to the large number of employees who work in these companies and the difficulty of maintaining distance measures in the meat processing tasks. In addition, slaughterhouses create a very conducive environment for transmission. “They are cold areas that facilitate the survival of the virus in the environment. The covid is compromised from 30 degrees and the work environment in these factories is always below ", pointed out to this newspaper the epidemiologist Ignacio Rosell.
But there is another factor that explains the rebound in these companies: a part of the cases belongs to existing transmission chains at least since April, when these slaughterhouses had not yet restarted their activity. "By doing more PCR tests now, we are detecting them. When we have done the epidemiological surveys, we have realized that in many of these infected the first symptoms appeared in April. Then they have spread to their families. They are transmission chains that have been maintained over time, there has not been an explosive rebound, which would be worrying. Right now, all the close contacts have been identified and the situation is contained," explained the sources consulted... ]
[ Relaxation of distance measures is another concern. "Society has relaxed security measures a bit and it is possible that, without knowing it, chains of transmission of the virus will be created," the manager of the health regions of Lleida and the Alt Pirineu i Aran, Divina, admitted to Efe this week. Farreny. At the moment, the CCAA are managing to follow and track all cases of new infected because the daily number is manageable. Ensuring that this monitoring does not overflow is going to be the nightmare of epidemiologists and Primary Care in the coming months. ]
I disagree: more than a bit
[Spanish] https://www.elconfidencial.com/tecn...navirus-cataluna-generalitat-covid19_2612600/
Daily infections in 4 meat companies: what is happening in the Lleida [Catalonia, Spain] outbreak?
https://translate.google.es/translate?sl=es&tl=en&u=https://www.elconfidencial.com/tecnologia/ciencia/2020-05-27/lleida-coronavirus-cataluna-generalitat-covid19_2612600/
[ Lleida went from having a cumulative incidence rate in the last seven days from 12.1 cases per 100,000 inhabitants to 42.7 cases on May 22. For a province of just 430,000 inhabitants, the data is a serious wake-up call...
The Health Department of the Generalitat recognized this week that the reason for the rebound is due to four fronts: new cases in residences, in health personnel, in slaughterhouses and at a birthday party with 20 people. However, the most unexpected is that produced in various meat companies in the province. "There are a total of four companies, but I prefer not to give their names. We are seeing a daily drip of infections from workers of these companies, about 3-4 cases a day. And also from their families. The rest of the cases are normal. No we are seeing more incidence in nursing homes or health personnel than expected compared to other Autonomous Communities," explains a health source familiar with the situation in Lleida who asks for anonymity...
This same source indicates that the problem of positives in meat companies has a double aspect. On the one hand, they are jobs with a high risk of contagion due to the large number of employees who work in these companies and the difficulty of maintaining distance measures in the meat processing tasks. In addition, slaughterhouses create a very conducive environment for transmission. “They are cold areas that facilitate the survival of the virus in the environment. The covid is compromised from 30 degrees and the work environment in these factories is always below ", pointed out to this newspaper the epidemiologist Ignacio Rosell.
But there is another factor that explains the rebound in these companies: a part of the cases belongs to existing transmission chains at least since April, when these slaughterhouses had not yet restarted their activity. "By doing more PCR tests now, we are detecting them. When we have done the epidemiological surveys, we have realized that in many of these infected the first symptoms appeared in April. Then they have spread to their families. They are transmission chains that have been maintained over time, there has not been an explosive rebound, which would be worrying. Right now, all the close contacts have been identified and the situation is contained," explained the sources consulted... ]
[ Relaxation of distance measures is another concern. "Society has relaxed security measures a bit and it is possible that, without knowing it, chains of transmission of the virus will be created," the manager of the health regions of Lleida and the Alt Pirineu i Aran, Divina, admitted to Efe this week. Farreny. At the moment, the CCAA are managing to follow and track all cases of new infected because the daily number is manageable. Ensuring that this monitoring does not overflow is going to be the nightmare of epidemiologists and Primary Care in the coming months. ]
I disagree: more than a bit
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It shows at which precise level the viral proteins may interfere with the interferon signaling.
maty
Major Contributor
COVID-19 treatment in Korea cost $57,562 per critically-ill, bill charged on state
https://pulsenews.co.kr/view.php?year=2020&no=471089
[ It took an average 70 million won ($57,562) for intensive care for a patient under critical condition from COVID-19, costing South Korea anywhere between 90.4 billion won to 98.5 billion won as the bill to cure the infectious disease is entirely covered by the state.
According to National Health Insurance Service (NHIS), the average hospital bill for treating a severely-ill patient came to 70 million won - patients that need intensive care 11.96 million won, and patients with mild symptoms 3.31 million won at medical clinics and 4.78 million won at general hospitals... ]
If I remember correctly, in Spain it is a little over 50,000 €. Of course, covered by the Spanish public health.
https://pulsenews.co.kr/view.php?year=2020&no=471089
[ It took an average 70 million won ($57,562) for intensive care for a patient under critical condition from COVID-19, costing South Korea anywhere between 90.4 billion won to 98.5 billion won as the bill to cure the infectious disease is entirely covered by the state.
According to National Health Insurance Service (NHIS), the average hospital bill for treating a severely-ill patient came to 70 million won - patients that need intensive care 11.96 million won, and patients with mild symptoms 3.31 million won at medical clinics and 4.78 million won at general hospitals... ]
If I remember correctly, in Spain it is a little over 50,000 €. Of course, covered by the Spanish public health.
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