Regarding atherosclerosis, there are several risk factors that includes life-style. But even given that you are a non-smoker, eat healthy and do your work-out, there is a significant genetic component as well. Some people just have higher cholesterol levels. I had quite normal levels when tested, but I am now on statins and levels of the bad ones are now way below the normal levels, which are good. Statins may have their side-effects (mostly with sudden needs to go to the loo) but they can actually help both stabilise and reduce plaques and even "heal" blood vessels.
The process of atherosclerosis includes inflammation as a main component, and inflammatory processes are quite interesting in this regard. Higher than normal inflammations markers may include causes such as stress and infections. I myself had an almost one-year cough 2018-2019 that eventually was cured with one week antibiotics - symptoms similar to C. pneumoniae infection. This occurred at the same time I got my heart symtoms. This pathogen is an obligate intracellular bacterium that has been found both in lungs and heart tissue. There are several publications of this pathogen and atherosclerosis, but no conclusive evidence for it to be involved in atherosclerosis. But one thing is clear though. It can cause long-lasting low-level infections with increased inflammatory markers which in no way should be good for your heart and vessels. It has also been shown to induce poor antibody response.
In Sweden there was also 16 cases of sudden deaths among orienteers some years ago, caused by heart arrest. This was a bit alarming, since no other sport at the time did have so many deaths within that time period. The real cause for the sudden increase in deaths was never found, but infections that spread within the community that exercised this sport was suspected. Both C. pneumoniae and Bartonella was suggested. One action was to treat the orienteers with antibiotics as prevention and after that no more deaths were observed. No clear evidence for what really caused the increase and disappearance of these deaths was however found.
So besides eating well and exercise, sleeping good is important. Stress over longer time periods must be avoided. And more research is needed for infections, including better diagnostic methods, for their involvement in inflammation and atherosclerosis.
The process of atherosclerosis includes inflammation as a main component, and inflammatory processes are quite interesting in this regard. Higher than normal inflammations markers may include causes such as stress and infections. I myself had an almost one-year cough 2018-2019 that eventually was cured with one week antibiotics - symptoms similar to C. pneumoniae infection. This occurred at the same time I got my heart symtoms. This pathogen is an obligate intracellular bacterium that has been found both in lungs and heart tissue. There are several publications of this pathogen and atherosclerosis, but no conclusive evidence for it to be involved in atherosclerosis. But one thing is clear though. It can cause long-lasting low-level infections with increased inflammatory markers which in no way should be good for your heart and vessels. It has also been shown to induce poor antibody response.
In Sweden there was also 16 cases of sudden deaths among orienteers some years ago, caused by heart arrest. This was a bit alarming, since no other sport at the time did have so many deaths within that time period. The real cause for the sudden increase in deaths was never found, but infections that spread within the community that exercised this sport was suspected. Both C. pneumoniae and Bartonella was suggested. One action was to treat the orienteers with antibiotics as prevention and after that no more deaths were observed. No clear evidence for what really caused the increase and disappearance of these deaths was however found.
So besides eating well and exercise, sleeping good is important. Stress over longer time periods must be avoided. And more research is needed for infections, including better diagnostic methods, for their involvement in inflammation and atherosclerosis.
Atherosclerosis by Virus Infection—A Short Review - PMC
Atherosclerosis manifests by the thickening of artery walls and their narrowed channels through the accumulation of plaque. It is one of the most important indicators of cardiovascular disease. It can be caused by various factors, such as smoking, a ...
www.ncbi.nlm.nih.gov