Hah, that's a setup I am strongly considering. How do you like it?
I'm an amateur and don't know much audio theory, so can only give you my subjective impression. Excuse my lack of, or wrong choice of, terminology.
I love the setup, much much better than my previous setup which consisted of JDS The Element and Edifier S1000DB. It's just a joy to use.
The JDS The Element had clear channel imbalance at lower volume which was very annoying, but the EX5 with it's digital volume control doesn't. Although people at the time were applauding the build quality of The Element, I actually prefer the build quality of the EX5. It's also much nicer having the power adapter built into the DAC/AMP instead of an outside power brick. The ability to adjust volume, mute and switch between headphones and speakers with the remote is great. And getting a display is just awesome, it just makes the Element seem like old tech. Don't get me wrong, the Element served me well, but looking back I think it's overpriced. Considering what's out there I would never get an Element 2. IMO JDS needs to up their game. And they're crazy expensive in Europe now.
People were complaining about the EX5 getting hot. I never found it to be an issue, mine gets pleasantly warm and I have never been worried it would overheat.
I had a few minor gripes with the EX5 though, and wrote about them in the EX5 thread. The volume knob is smooth, so it's slightly slippery when you turn it. Would be nicer if it had a more grippy surface. Also the knob is pretty big in diameter so unless you have it elevated, you can't get a proper grip underneath it with your fingers because the table surface is in the way. I think a narrow volume knob like in the RME ADI-2 FS would be better. Finally I find that you have to point the remote straight at the DAC/AMP for it to register, I would prefer if it was much more lenient (like I could point the remote straight up and it would still register the input).
About the speakers, I'm overall happy with them. At first I had the speakers placed low, close to my table and was a bit underwhelmed by the sound. But then I got some proper stands, lifted them up so the tweeter was at ear height and it helped tremendously, it sounded much less muffled. I also put some more distance between the speakers which helped with the imaging. I don't remember the exact numbers but Kali actually recommends significant more distance between their LP line of speakers than their IN line of speakers. So I guess one should consider the IN line of speakers if they want to place the speakers close together.
One thing I noticed is that with the Edifiers I would always be aware of which speaker the sound was coming from. If I leaned one way I was clearly aware that the sound was coming from one speaker, leaned the other way I noticed it from the other. It was annoying. But with these Kalis I don't notice such localization. Don't get me wrong, the stereo imaging is great, but when I lean to the left it's not like the sound shifts and is suddenly clearly coming from a pin point location in the left speaker.
I'm a bit underwhelmed with the bass response, it seemed to me the Edifiers had more. But I think perhaps the Edifiers just had a boosted low frequency response, and I had gotten used to it? Also the Kalis actually have a rear dip switch where you can boost the low frequency with +2db if you want, and I haven't played with that yet. Everyone else is saying the low frequency response is great, so I'm probably wrong. I think on paper the LP6s should have more low frequency output.
Finally I find the LP6s are a bit too big for my desk. In the future I think I'll aim to get some smaller speakers. Furthermore, while looks are subjective, I don't think they're that pretty compared to something like say the KEF LF50 Meta. It doesn't matter too much to me though, I'm more about function and they're not hideous. They look like a serious, professional piece of kit.