Is the contrary possible as well? Get the 4 ohm version and occasionnaly use it with 8 ohm-rated speakers?
It is possible, but the output will be around 50W.
Below are the answers I got from 3e audio in other forums.
The only difference between the 8Ω version and the 4Ω version is the output voltage setting of the power supply, and it seems that you can switch to either model simply by adjusting the voltage. However, it is necessary to change the DSP firmware.
In actual use, it is often used with an output of up to about 10W, and I think it does not matter whether you purchase 4Ω or 8Ω.
---- 3e audio said ----
Hope this help understand which options you should go for.
in other word, you still can run at 4ohm on 8ohm model,but should not kill very high output as it may over power supply capability(amplifier is constant voltage output,the lower load the higher current draw from power supply).
also,the rail voltage configuration is changeable by DSP F/W,that is say,you can change 37V to 44V or 44V back to 37V for some reason want to pair different speaker, or getting more head room or want less power loss.