Thanks for doing the calculation, my amp is about a 20 times gain too. still, I often use a gain at 2 times at the preamp. Those quick calculations are simplistic, but I agree that 4 volts is enough for most use cases. As you know, we don't normally listen at 1 m, but more importantly, peaks in music, when not overly compresses are at least 20 dB higher than the average level, sometime more. So in your example if the momentary highest transients generate 300 Watts you are really getting a listening level of 90 dB, at 1M, 84 dB at 2m, 78dB at 4 m, with some very dynamic recordings, or movies, the crest factor is even higher. And yes, I should add the 3 dBs to this for 2 speakers. Now yes, I agree that when 4 V is not enough, your gain structure is not optimal, but it's also OK to not be optimal, sometimes you want to listen very quiet as background music, sometime you push it hard, sometimes, for some weird reason, this website or this youtube video, is streaming extremely quiet, there are plenty of situation in life where you want to stop being an audiophile and not worry, but I look at my preamp volume and it's maxed out. It is what it is, headroom is always nice.
Edit: that said, I believe we are entering the "derailing thread" territory that Amir was mentioning. Merry Christmas to all.