I'm most interested in this from a "marijuana as tweak" point of view. It seems that most of us who dig high end audio can be a little but like experience junkies pursuing that sometimes-elusive state of being totally immersed in the music, digging all the details, toe-tapping, slamming, whatever. Any trick you have that gets you into that hyper-attentive state will significantly enhance your audio experience. Someone upthread suggested a breathing technique, I had suggested meditation.
But come combinations of THC and CBD also seem to be a kind of 'cheat'. Far more than alcohol or caffeine, for me. Those are the only substances I've tried.
(forgive me if I repeat myself, but the "enjoying audio more" angle remains my primary interest in the thread)