Funny how apt your spell check analogy actually is. The source is sending several things, typically one is power, and also data. That data is transmitted in the analog domain, and interpreted at the receiving end. It is in the interpretation stage that errors can be introduced.
Jitterbug goes somewhere in front of the DAC not after.
You are making a common mistake: the fact that digital data gets transmitted
electrically (as voltages) does not mean it gets transmitted "
in the analogue domain." The data remains digital, which is to say binary, which in turn means that the level of precision required to determine if a 1 or 0 is being transmitted across a wire is far less than the level of precision required to reproduce an analogue signal perfectly across a wire. If digital data were actually transmitted in analogue form (as opposed to merely electrical form), then none of us would even be having this conversation because there would be no internet.
More to the point, there are already tests out there online where people have done what you are asking for: run "normal," noisy USB sources into DACs with and without USB isolator products in the chain, to see the impact on the analogue output of the DAC. There's a really good one that uses the "eye patterns" that are a favorite among audiophile proponents of these devices but I can't lay my hands on it at the moment (I could've sworn
@Archimago did such a test but so far I've been unable to find it over at his blog site).
But our own Amir ran such a test a couple of years ago, albeit without eye patterns, using as a source a typical laptop's USB output:
https://www.audiosciencereview.com/...s-of-intona-usb-isolator-for-audio-dacs.2616/
He found that if you use a terrible DAC, one USB isolator helped with low-frequency noise but not with jitter. The other USB isolator didn't help at all, and in fact added extra junk into the signal. Given that the cheapest USB isolator cost more than the crappy DAC in question, the lesson seems clear: competently designed DACs are more than capable of coping with a noisy USB source, and the USB isolators make no difference. The only scenario in which an isolator made a difference was if you paired a bad $150 DAC with a $229 isolator, which is of course silly since you can just buy a properly designed DAC for less than the combined price of those two and have your "USB isolation" built in to the DAC.