Also what about a solution where I get Neumanns or Genelecs and pair them with 2 cheap subwoofers like Presonus?
I guess that depends on your priorities. The recommended Kali IN8 + a sub (or two) + a miniDSP + measurement mic would probably get you very far on sound quality alone.
However going for Neumann or Genelec from the start may help with upgraditis
, and you could always add subs later.
One of the benefits of some Genelec (73xx / 83xx) and Neumann (KH 80 / KH 150 / or any analog Neumann paired with KH 750 sub) setups is that they have built-in DSP and can be used for room EQ with the additional kits (Genelec GLM / Neumann MA-1).
Your main criteria should probably be SPL capability and driver integration though, which will be largely dictated by listening distance. For large listening distances and big rooms (like in a large HT) you need more SPL (which typically means bigger drivers), while for nearfield listening you need smaller drivers (or coaxials) so they integrate well at close distance. From that perspective Kali IN series might indeed be a nice (budget) compromise.
Good luck in your search!