The Harman target is measured with reference to a dummy head and pinna, i.e. the headphones they used in the study were measured on their dummy, and the target response was calibrated based on measurements taken on this dummy. They've developed their pinna with a lot of care, but nevertheless their target response will not be correct for you if your head and pinnae are significantly dissimilar to Harman's.
Also, the Harman target curve is not flat in the bass. There's actually a 4dB shelf, which is lacking in the HD650s. These would be considered lean headphones with reference to the Harman curve.
EDIT: OE2017 in the graph below is the current Harman curve for over-ear headphones I believe:
View attachment 14391
Here's my attempt at Harman curve with HE-560s, measured: