When I test amplifiers, I test first at full power, i.e. just below visible clipping on the 'scope, then at 1W and 100mW, and check that distortion is still low, and any increase in the number is purely a function of noise and not anything else like crossover distortion. One disadvantage of measuring distortion using a spectrum display is that one doesn't see what the residual looks like, which can show up crossover distortion very obviously. Equally, a THD meter won't show the individual harmonics or power supply artefacts like a spectrum, so both are really needed to characterise an amplifier fully. Depending on how deep I want to go, I also measure at different frequencies and loads, but if I'm just checking an amp after repair, then 1kHz & 10kHz 8ohm at full power will generally tell me if it's OK.
S