From what is measured so far by Amir, in terms of audio engineering, Topping (and equivalent brands like SMSL, Sabaj) are top notch.
More recents and expensive gears in those brands are usually more powerful and offer additional features (more inputs, outputs, connectors, ...).
In terms of audibility, in most of the case, difference between them are hard to perceive because they are below our audibility threshold.
The difference may be noticeable if you listen at high level or/and specific recordings with low frequencies.
The less powerful ones won't be able to reach very high volume (and without distortion) or would go into protection sooner.