What science areas?
And, it's usually just blind testing being requested, not double blind.
This is a science site after all...don't get angry when people are asked to back up what are typically very strident and 'night and day differences' types of subjective posts, with no attempt to control anything.
Well, I wasn't talking about "night & day" differences, just enough to notice a loss of low-level resolution. I don't hear a difference between Flac and Apple Lossless, FWIW. I do appreciate that gear gets measured properly here.
I have a hard time listening to LPs because of the continuous loss of fidelity as the stylus approaches the deadwax. Michael Fremer seems to think that is "no big". But compared to lossy vs lossless, that is a gross distortion. I haven't spent time ABXing anything, don't have the means or the desire. My audio comparisons have been all "sighted", but having spent a decade as a recordist [recording engineer is too elevated a term for what I was doing] I can tell you that taking the headphones off and walking into the room where the music was playing was like walking into a different world. What I was recording was "Classical" music [weird term, properly speaking the term only applies to Haydn, Mozart, Beethoven and contemporaries], so usually just two microphones in ORTF configuration, and yes, the whole chain would be altering the sound. But the most sonically obvious difference was via swapping microphones. Microphones, like phono cartridges, like speakers, are transducers, and they are all obviously coloring and distorting the sound.
I would expect that ABXing lossy vs. lossless would usually result in "I dunno" as they would be very close, particularly as most recorded music is compressed and sonically compromised in the first place. ABXing "Florence & The Machine" would probably result in "no difference", an uncompressed recording of Mahler's Third Symphony would be more likely to reveal a difference.
In any case, the version I store on the computer is the version I store on the DAP as the cost of memory is so cheap right now.