I generally don't have an issue with changes in gender or ethnicity in casting, but to cast Salvor Hardin as a female is problematic for me. I've read Foundation multiple times and he's such an important character I don't know how well it'll work, but I'm certainly going to watch.
I also hope nobody attempts to do Stranger, as it is an important book in my life An almost impossible task I think. But I guess someone will try and probably do a job on it like Childhood's End, which was complete garbage.