Well.... about 3 years ago I "discovered" the Computer Audio forum (now renamed Audiophile Style) and there were numerous voodoo threads on there about tweaking your computer for better audio.
There were threads on different RAM memory modules that made massive differences (ECC memory from a specific brand was best)
Threads on different motherboards, CPU's, Sata cables, network cards, usb cards, LPS power supplies, SSD disk drives etc making massive differences (all cumulative of course!!!)
And of course threads on all types of network tweaks: reclocking routers and switches, specific routers/switches, different ethernet cables, power supplies attached to routers, switches and media convertors, OS level network changes etc making massive differences.
All of this stuff is expensive... check out the stuff from JCAT.
Its bloody hard to do a real unsighted test/instantaneous switching for comparsion when your have to spend several minutes swapping out RAM, hard drives etc.
The only "obvious to anyone" tweaks that might make a difference would be media conversion (i.e. ethernet -> fibre -> ethernet) and an LPS on the endpoint computer (i.e. that which plugs into the DAC).
I am now 100% PC/USB DAC based and aside from implementing the above two tweaks (to soothe my paranoia, less than $US 300 spent) the other simple thing is to have a two PC system: a big grunter storing your files/upsampling/EQ'ing not in your room and a low powered, silent diskless PC that boots into memory off a USB stick that is the end point into your DAC.
So people ended up with topologies like the one below to get music from their router to the DAC (including 7 LPS's, reclocked switches, high end ethernet cables, PS audio perfectwave, Chord DAC's etc... the last two being ASR favourites!!!).
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