In addition to the motherboard drivers, there is also a guy maintaining universal Reaktek drivers that should work with all motherboard onboard Realtek audio chipsets. He has driver releases @
https://github.com/pal1000/Realtek-UAD-generic
They are more up to date if your motherboard manufacturer is slacking there, and could possibly contain some bug/vulnerability fixes.
They are also somewhat slimmed down compared to manufacturer releases and fully compatible with the Realtek UAD console app which is nice.
Might be a good idea to get some measurement comparison to ensure his universal drivers are working correctly.
I mentioned the GPU noise affecting onboard audio in another thread and had people absolutely insist that it wasn't the GPU and other USB devices and devices connected to other AC outlets in the house were causing it. Be ready for them to show up here too.
One of my favourite forms of GPU noise interference is scrolling a webpage causing a small framebuffer processing spike that makes a scratching noise come through the onboard audio.