Yes, not only fine, but that's the way to do it.
Your amp's performance may be degraded slightly, depending upon the quality of the amp, at 8 o'clock-ish, or 4 o'clock-ish, but will be good at 1 o'clock-ish. (And may be perfect also at 8 o'clock-ish, or 4 o'clock-ish.)
With the S2D set to...