I tried to simulate that. This is the best I could come up with in 4 x 5m and a reasonable listening position.
I assume this could be EQed to nearly flat, as there are no nulls below 160 Hz?
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But this example also shows the limits of a single sub, if one switches on the results for positions around the point measurement from above.
Now there are differences of up to 12 dB from positions half a meter apart.
That puts things into perspective a bit (as I grew quite envious already ;-)
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Yes, you are certainly likely to be limited to a single seat sweet spot with only one sub, and you are quite lucky if you can both position your sub in the optimal place and have the sweetspot in a good place too. But it isn't impossible.