I have another PC upstairs that's primarily for recording music, it has a GeForce 1070. I hadn't considered swapping it out to see if the problem persists. Issue with that is that even if it shows that it's a GPU or motherboard issue, I'm not really inclined to drop several hundred (or almost a thousand, thanks GPU price inflation) dollars on a replacement if a much less expensive power conditioner/filter might also fix the issue (or if I can just keep running un-earthed, which is a risk, but a minor one).