HiFiMan fan here.. The HE-6 has the crown of best HiFiMan and perhaps top 5 headphones out there . I haven't heard the HE-6SE so can't opine.HifiMan HE4XX. One of their most affordable models, and according to professional measurements and the best science we currently have, they are also HifiMan's (and Drop's) best sounding headphone. Those blinded by pricing bias will tell you otherwise of course