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What you need to know about the virus in China "2019 Novel Coronavirus (2019-nCoV)"

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Like this thread? Wait, I can go back to ignoring it...
If it's not helpful to you , ignore it.

If it serves anybody even as a coping mechanism, well that's why iv tried so hard to moderate it and keep it open.
 
Problem is there's no exit strategy from all this lockdown shit.

Nobody knows how to get out of what we've all stepped in.
Yes, it's going to be tough to get out of this, especially in the US, because of our highly litigious society. Just watch the TV ads that air every night on TV, in which law firms solicit clients to go after almost any industry you can think of. Every major corporation has a cadre of defense attorneys who are now burning the midnight oil about how they can restart their operations, while protecting themselves from legal liability if a single person contracts covid-19 at one of their restaurants or other retail businesses and has a terrible outcome. How much money will companies have to spend in order to try to protect themselves from liability? How long will it take them to come up with some viable and sustainable business model? I could even see the government, in an attempt to support an economic resurgence, coming up with some program of limiting liability for businesses who forge ahead with operations.
 
How sewage could reveal true scale of coronavirus outbreak
https://www.nature.com/articles/d41586-020-00973-x

d41586-020-00973-x_17851422.jpg


[ So far, researchers have found traces of the virus in the Netherlands, the United States and Sweden...

But to quantify the scale of infection in a population from wastewater samples, researchers say the groups will need to find out how much viral RNA is excreted in faeces, and extrapolate the number of infected people in a population from concentrations of viral RNA in wastewater samples... ]

[ Studies have also shown that SARS-CoV-2 can appear in faeces within three days of infection, which is much sooner than the time taken for people to develop symptoms severe enough for them to seek hospital care - up to two weeks - and get an official diagnosis, says Tamar Kohn, an environmental virologist at the Swiss Federal Institute of Technology in Lausanne... “Seven to ten days can make a lot of difference in the severity of this outbreak.” ]
 
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Coronavirus: conclusiones de las primeras autopsias en muertos con Covid-19
[Spanish] https://www.redaccionmedica.com/sec...imeras-autopsias-en-muertos-con-covid-19-9912

Coronavirus: conclusions of the first autopsies in dead with Covid-19
https://translate.google.es/translate?sl=es&tl=en&u=https://www.redaccionmedica.com/secciones/sanidad-hoy/coronavirus-conclusiones-de-las-primeras-autopsias-en-muertos-con-covid-19-9912

[ The Milan Polyclinic Hospital has begun to perform autopsies on patients with Covid-19 coronavirus. So far, a total of 50 have been performed, in almost all cases targeting the lungs, and it is the world's largest case study, as results from only three minimally invasive autopsies were published in China... ]

[ Possible cause of respiratory failure caused by Covid-19

As indicated in the study, Covid-19 classically gives anosmia and ageusia: it could reach the brainstem trans-synaptically starting from the peripheral nerve endings of the olfactory or lingual nerve. In this scenario, "respiratory failure could be caused by direct virus damage to the brainstem nuclei."

One of the authors points out that “in the blood of patients with Covid-19 infection there is a very high number of endothelial cells (expression of endothelial damage caused directly by the virus) and that these cells trigger a cytokine storm that recruits mainly macrophages”. It is also for this reason "that high doses of cortisone can work."

In this sense, "an anticomplement drug (narsoplimab) was used in 6 patients that dramatically reduced the number of circulating plasma endothelial cells (but endpoints were not specified)," they concluded. ]
 
My best friend, 56, lives in London England (I'm in Toronto). He's been tormented over the last couple weeks with COVID and just sent me a picture showing he's in the hospital. Frightening! Though perhaps a silver lining is getting in there before the system is more overloaded.
 
Coronavirus: conclusiones de las primeras autopsias en muertos con Covid-19
[Spanish] https://www.redaccionmedica.com/sec...imeras-autopsias-en-muertos-con-covid-19-9912

Coronavirus: conclusions of the first autopsies in dead with Covid-19
https://translate.google.es/translate?sl=es&tl=en&u=https://www.redaccionmedica.com/secciones/sanidad-hoy/coronavirus-conclusiones-de-las-primeras-autopsias-en-muertos-con-covid-19-9912

[ The Milan Polyclinic Hospital has begun to perform autopsies on patients with Covid-19 coronavirus. So far, a total of 50 have been performed, in almost all cases targeting the lungs, and it is the world's largest case study, as results from only three minimally invasive autopsies were published in China... ]

[ Possible cause of respiratory failure caused by Covid-19

As indicated in the study, Covid-19 classically gives anosmia and ageusia: it could reach the brainstem trans-synaptically starting from the peripheral nerve endings of the olfactory or lingual nerve. In this scenario, "respiratory failure could be caused by direct virus damage to the brainstem nuclei."

One of the authors points out that “in the blood of patients with Covid-19 infection there is a very high number of endothelial cells (expression of endothelial damage caused directly by the virus) and that these cells trigger a cytokine storm that recruits mainly macrophages”. It is also for this reason "that high doses of cortisone can work."

In this sense, "an anticomplement drug (narsoplimab) was used in 6 patients that dramatically reduced the number of circulating plasma endothelial cells (but endpoints were not specified)," they concluded. ]

This is what I suspect will happen. We'll come up with improved palliative treatments for the virus. They may or may not slow down the virus, but will provide protocols for optimal treatment to improve survival rate. People will still die, but there will be a higher % of survivals. I've no doubt that there are studies in progress assessing the outcomes. The problem is that they take time to be done properly, thus the need to 'flatten the curve'.

And yes, improvements in treatment will hasten the end of the full lockdown which no one argues should go on any longer than needed although it's unlikely to be the end of the need for dealing with the virus through testing, isolation, etc.
 
My best friend, 56, lives in London England (I'm in Toronto). He's been tormented over the last couple weeks with COVID and just sent me a picture showing he's in the hospital. Frightening! Though perhaps a silver lining is getting in there before the system is more overloaded.
I'm sorry mate , thats close to home . It's really hard when people you love are in distress and your so far away.
 
In these confusing times, when it’s hard to know who to listen to, I would like to make a suggestion.

Please listen to your country’s top epidemiologists. They are trying to help you. They know more about this disease than your personal doctor, someone else’s doctor, the economists, the politicians, and anyone on the Internet.
 
My best friend, 56, lives in London England (I'm in Toronto). He's been tormented over the last couple weeks with COVID and just sent me a picture showing he's in the hospital. Frightening! Though perhaps a silver lining is getting in there before the system is more overloaded.
Sorry to hear about your friend, hope he pulls through.
 
In the end this is mathematics, statistics. Spain has risen very fast and will also fall rapidly. Other countries will take longer but in the end the statistics will be similar (per million inhabitants) in terms of number of infected.

The difference will be in the intensity of the confinement. The current one in Spain is very strict and that will, I think, make us go down even faster.

The official deads by the end of the April, about 20,000. Until now the real ones I estimate now to be 80% more, but thanks to the fact that the hospitals will be less saturated, this overestimation will decrease as we can attend to other patients who suffer other illnesses. The faster the fall, the lower the number of deaths. For now it is unknown.

Other countries count the death toll much worse, I suppose, to calm the population. It is a mistake in our societies because it will increase distrust of the authorities' recommendations.
 
I watched a news release a few days ago. A restaurant owners association stated that according to their figures 18% of the closed restaurants will close for business permanently. In Canada. In a month that figure will be worse and in several months the closure rate will be horrendous.

But we need a control. i.e. a comparison to the extremely high failure rate of restaurants in general - (at least in the US) small biz has the highest failure rate and of all types of small biz, restaurants are the highest.
 
Problem is there's no exit strategy from all this lockdown shit.

Nobody knows how to get out of what we've all stepped in.

Not sure what you mean - the Fed certainly has some ideas about it.

The Eurozone countries are following a different path than the US - e.g. by requiring co.s to not fire workers and subsidizing them to that effect
 
In these confusing times, when it’s hard to know who to listen to, I would like to make a suggestion.

Please listen to your country’s top epidemiologists. They are trying to help you. They know more about this disease than your personal doctor, someone else’s doctor, the economists, the politicians, and anyone on the Internet.

True, but you'd hope that your PCP is carefully following their clippings service on this (not to mention other things)...
 
In these confusing times, when it’s hard to know who to listen to, I would like to make a suggestion.

Please listen to your country’s top epidemiologists. They are trying to help you. They know more about this disease than your personal doctor, someone else’s doctor, the economists, the politicians, and anyone on the Internet.
No, no, no. These central planning infectious disease experts are NOT your friend if you become seriously ill with covid-19. Fauci has already scared way too many doctors off of trying hydroxychloroquine for seriously ill covid-19 patients. I'll bet you 10 to 1 that all these poor folks dying in NYC were not offered or prescribed hydroxychloroquine early in their illness. Fauci and his counterparts are completely focused on conducting controlled clinical trials and treatment protocols, which will take a year or more. Meanwhile, you die. They do not care about your individual case. If at all possible, you need to have your own local primary care doctor who will fight for you to receive available treatment modalities. Even if they do not "know more" about the virus than Fauci, they are YOUR doctor and much more willing to fight for you to at least try a treatment that may arrest or slow the viral replication. I am planning to contact my doctor tomorrow to advise him that if I become seriously ill with covid-19, I am willing to accept any risks of hydroxychloroquine and would like to take it early in my illness, so as to possibly preclude hospitalization.
 
No, no, no. These central planning infectious disease experts are NOT your friend if you become seriously ill with covid-19. Fauci has already scared way too many doctors off of trying hydroxychloroquine for seriously ill covid-19 patients. I'll bet you 10 to 1 that all these poor folks dying in NYC were not offered or prescribed hydroxychloroquine early in their illness. Fauci and his counterparts are completely focused on conducting controlled clinical trials and treatment protocols, which will take a year or more. Meanwhile, you die. They do not care about your individual case. If at all possible, you need to have your own local primary care doctor who will fight for you to receive available treatment modalities. Even if they do not "know more" about the virus than Fauci, they are YOUR doctor and much more willing to fight for you to at least try a treatment that may arrest or slow the viral replication. I am planning to contact my doctor tomorrow to advise him that if I become seriously ill with covid-19, I am willing to accept any risks of hydroxychloroquine and would like to take it early in my illness, so as to possibly preclude hospitalization.

I believe the point of the message is that people don't start acquiring and hoarding hydroxychloroquine (and in general other drugs) thus keeping it away from patients who actually need it based on evidence. I would expect people like Fauci to care more about the general welfare versus individual cases.
 
I believe the point of the message is that people don't start acquiring and hoarding hydroxychloroquine (and in general other drugs) thus keeping it away from patients who actually need it based on evidence. I would expect people like Fauci to care more about the general welfare versus individual cases.
Well, of course, lay people should not be able to acquire and hoard it. That's not what I'm even talking about. I'm saying that it should be prescribeable by community physicians for patients that are going down with covid-19, so as to attempt to preclude having to be admitted. It's not like it's some wildly expensive experimental drug; it is generically available and has been prescribed since 1945. Apparently, at this point, according to a local pharmacy where I asked, it is locked down by the CDC and they say that they cannot get it from wholesalers. I asked, well what about people who need it for their other conditions for which they take it, and their answer was that they "have to go through the CDC"! WTH?
 
It is prescribed here in the Netherlands but thus far it does not seem to of benefit. For a third of the patients its use had to be stopped because it degraded their cardiac performance.
 
I am glad that here in the Netherlands politicians listen to scientists. Fauci seems to be just about the only adult in the room.

A search will reveal a lot of statements Dr. Fauci made a month or two ago were opposite what he says now, and he is not in agreement with some of the leading doctors from institutions like Johns-Hopkins and such let alone some of the front-line care providers (like my wife). He sounds good, though, and that is not without merit in times like these. And if you look at what our administration has actually done vs. what leaders spout (on both sides) it is generally in line with the medical professionals.

I'll try to ignore this again, sorry Thomas, this is very personal in my family and circle of friends.
 
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