Predicted in room response was a nice gentle slope down - I guess that is what I hoped I’d hear
This is unfortunately not what you will hear with any speaker.
It is simply a side effect and often overly weighted, likely as folks can take these type of measurements at home and hobby up(I do it). Also Dirac and the like have us focused on this as Dirac can adjust in room responses for $.
That is why there is a spinorama, which consists of measurements of major importance.
The predicted in room response is really just to show some correlation between the Spinorama and a real room. It is not what is heard, the hearing of which is happening with a much more complex system that is not even remotely as limited as the in room steady state. (your ears, brain & mind)
I have had a hard time being able to tell exactly where sibilance will come from in the test of your THX-365C, though the measurements to my eye are meh - in terms of the horizontal off axis which you will hear bouncing off the walls and recombining in some various forms with the direct sound whether you are sitting on axis or not. That said it is possible your copy has a defect, a bad tweeter or a lose part. Are you able to measure HD & some sort of gated response, also you could take a steady state in room and compare it with the prediction which could be fun.
As other stated the perception of sibilance can be sourced to a variety of issues. Is it there when you listen to content that you know was recorded without it? Many, many recordings contain sibilance and therefore any accurate replay will also contain it.
The location of a speaker in a cabinet or causing something nearby to resonate could also be a source.
Anecdotally, I have experienced extra sibilance it some speakers that appeared they would not have it, not sure why. Also some times I am far more bothered by it vs others again not sure why.
IMD and Doppler distortions are almost never published or measured well, they can be so complex and attempts to recreate them may far short of reality. (though, like HD tests they still are helpful to point in the right direction)