IMHO the 1kHz noise is caused by the 1ms USB fullspeed packets interval, not by a ground loop which the isolator is intended to break. The 1kHz noise may be improved by either a better power supply filter in the USB device, or perhaps a better generation of the ADC master clock from the USB clock which would have a heavy 1kHz USB packet component.Not only didn't help with my mic's 1kHz noise but increased it from -75 to -66 dB