Musicians should create the sound they want (using tubes or not) on their instruments only.
This is where tube distortion should be added.
If other instruments or voices also need 'tubeness' it should be done at that point with their own signal only.
Instruments/voices that don't have 'tubeness' added shouldn't have tube distortion added afterwards IF you are looking to reproduce the recording.
On reproduction with low distortion this recording should sound equally good as what was recorded (providing engineers didn't change things which they probably did in most cases).
One can choose to add 'tubeness' to get more personal pleasure. That's fine. Don't say it is 'better' as obviously there will be a difference between in and output signals. This won't be the case with low distortion amps.
It's a personal choice folks.
One should also realize that adding tubeness per instrument before mixing has a different result as adding 'tubeness' to the final signal which is an addition and tubeness is applied on the combined (added) signal of all instruments.
Whether one finds this pleasurable or not is another thing. Also there are many studios NOT using tubes everywhere and tape (which imparts its own thing) but most recordings are 'enhanced' with plugins to the channel they want. Mostly digital.
Don't get me wrong. I too design tube and non-tube based stuff. My views on 'lowest distortion is essential' obviously is not something I would claim.
People should (and do) have a choice in what they buy, use and prefer/like. There will always be manufacturing catering for it.
Regarding the 300b amp distortion.. I'll bet you can simulate it by using the transfer function of the amp AND increasing the output resistance of the SS amp in a similar way as the tube amp. I am pretty certain measurements will be the same and when tested blind will be indistinguishable.
Applying only the transfer function in DSP will not give the same results as the real deal because the output resistance combined with the impedance of the used speaker is also important and can not be simulated unless the output R and impedance plot of the used speaker are also simulated so will ONLY be valid in only that situation.
There is NO magic in tubes... there are free electrons floating around though but this is not magic but physics and is predictable and measurable.
End of 'tubes are bettaarrr' rant which is always based on sighted findings and is preference based.