It might be fine if you never launch the Home web app, but you may also run into what
@juzio encountered (though they didn't say which version of Windows they run on their computer?). Unfortunately, I think the only way to really know is to have a back up of your PEQ files, and launch Topping Tune. Last time I launched Topping Tune after checking out the web app, I lost all of my PEQ profiles, and ran into a weird issue where -- despite there being no PEQ profiles listed in Topping Tune or the web app -- my DX5 II itself showed 5 DevConfig profiles, and I had to do a factory reset to fix the problem.