I think the advantage of the LS50 is dispersion. It has much more uniform dispersion compared to the Sonos Five and since we hear a combination of reflected and direct sound that can make a difference. I think the highs will be more pronounced on the LS50 making it sound more detailed. Bass is probably a little better on the Sonos Fives. Plus Sonos uses DSP to boost the bass at lower volumes when we are less sensitive to bass. The LS50 might have the more refined sound you are looking for but I think you give up some dynamics.
My personal opinion. We carry Kef where I work and I like a lot of their models. The LS50 meta, LS50 wireless II, LSX II and LT, Q1 and Q3 never really impress me much. They lack dynamics. They have a nice sound but no oomph. It is not that I prefer boosted bass or highs. Just the opposite but when I hear these compared to other neutral speakers they just lack dynamics. I would defnitely recommend a sub with any of these models I mentioned.
I think they are trying to go too low with these small coaxial drivers. I think the models that have a seperate woofer are much better like the R3 Meta. If you can step up to the R3 and use a streaming amp like the WiiM Amp that would be a MUCH better combo. I would also try a streaming amp with some of the Revel or the new Ascilab. If you go active many of the studio monitors I think would give you the performance you desire. Neuman, Kali, Genelec, Adam, etc with a WiiM Pro plus. Most of the studio monitors do not win any awards for aesthetics though.
I really don't know too many other active speakers with Roon, Tidal or Qobuz connect and Airplay built in to the speaker. The only other one I can think of is the B&W formation Duo. Probably at the higher end of your range. I would try to listen first. B&W is not known for accurate speakers but if you like their sound that is all that matters. In general it is a good ideal to listen to speakers you are considering when possible. Take them and try them if the dealer allows. I know that is tough in many areas. I would also get the speakers from a place that has a good return policy. Things can sound different in your room.