How you will get 22 Channels Out? I guess with ADAT only, but than no 96kHz anymore possible on all Channels Out.
So i used the Second for additional 6 Chanel used the First one for 10 Channel TRS Outs and connected the second on SPDIF (2Channel 96kHz) and ADAT (4 Channels for 96kHz).
Thats makes 16 Channel @ 96kHz with usable Volumeknop on both Devices for TRS Outs (So i could change the Volume to an good Level let say -15dB and fineadjust on the Source, Streamer)
So a MOTU has 10 Analogue Outs TRS
8 Channels aviable at ADAT Out (48kHz only, 4 Channels 96kHz)
2 Channels on SPDIF Out
And i gues 2 more for Headphone Out on the Frontpannel.
So even without the second Motu you need DAC's with ADAT capabillity thats also cost Money and may be Sounds different so i used an second Motu for the same Quallity on analogue Outs with TRS
But you need to know even than you has to time align this Outs, on SPDIF and ADAT there is more Latancy to the second MOTU i need to add Delays on CamillaDSP for the first MOTU

Than i had all 16 Channels timealigned without drifting.
Also don't forget HDMI isn't known for less Jita so an HDSPe Card has an supression -50dB on Jita at AES Inputs

i like this option a lot.
But will measure how it will go on my Setup any day also my HDMI to 4 AES is work in Progress
Used the HDMI to i2S Board before on an RPI5 4 Channel I2S input