I lean against but am still intrigued.
I was intrigued enough to look at things, given I could drop a bit of money on gear this summer if I wanted. For me, it would be a bad decision, but that's because of my room. I am currently running Ascend Sierra LX, no sub, and they are 5' off the wall behind them. Flat to 20db is no problem, level wise, though the quality of bass below 35db is not great. It's there though.
If I had a conventional space? It would be tempting. Would I do it? I would lean towards yes, but it's pretty close. Close enough that I might change my mind as typing.
It would be hard to give up my current system because there was a lot of thought and decision making that went into it, the decisions and setting it up. Genelecs are a commodity product, there is no decision about how to integrate it with other components, it is what it is. That is subjective, but it is the case with me.
If I was going from 2.2, I would like the fact that I could ditch the subs. Don't get me wrong, I like a sub in my AV system, but "no sub" was my goal in my current system. No integration issues, and lots of floor space freed up. In a 12x12 room, maybe the dual subs will give you better bass though. I have (thankfully) never had to set things up in a square room since I started measuring, but I know there are issues.
How much improvement would I get that I personally would notice? Well, cleaner bass at the extreme low end, and I do put on organ music occasionally. For the rest? I know I will hear a 2db, will I hear a 1db difference? Not without A/B and a lot of concentration, based on past experience. Instrument location and separation are great, and I don't really hear much more that could be "locked down" in that area. Again, A/B probably, but absent that? Yeah, likely a bit, particularly in the bass.
Could I live with how they look? Well, sure! But nice wood cabinets are nice to look at. And given the main room of the house... I really would not want to heft those off the stands when not in use.
Stands. Most likely I would start with some end/side tables or DIY, until I confirmed the height I needed, then consider commercial stands. I've done that before, works fine for diagnostic purposes.
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Ok, so I would try the Phils with no sub, do some measures, and see what the bass mode situation was. If I could set things up for a single listening position and keep the bass from nulling at a frequency I cared about, then Genelec. OTOH, if there was a null I could not deal with, or if I wanted MORE than one listening position, then I would stick with dual subs and the Phils.
It's a tough choice, really. I don't think you can go wrong either way, but given a square room, 4 bass sources (two speakers and two subs) are way more likely to give you the ability to get the bass right. That's the biggest factor, but how important that factor is to you depends on you.