Yes when I've blind tested myself dacs with non standard filters are mildly detectable. That appears to be simply due to FR. Nothing exotic.
I actually don't like that DACs now offer these filters. I know it is offered because it is easy and looks like a feature to differentiate one product from another. I do have recording interfaces that have minimum phase filters, but they do that for lower latency. They also aren't exceptionally slow roll off filters like some that are available.
Of course cable resistance matters for DF and this is very measurable.
How much it matters also depends on the output R of the amplifier, the load impedance as well (and how much it varies).
DF would have to be worse than 10 to really make an audible difference though.
In your first example output impedance (amp plus cable) is dominated by the amplifier.
In your second example, it is dominated by the cable - but only because you've changed your gauge from a reasonable 14awg to a less useful 18awg. In other words - thin lamp cord.
The only rating of speaker cables is resistance - as long as you select low enough, then cables don't matter. I don't use smaller than 13, my current cables are 11 (2.5mmsq and 4mmsq)
Speaking of blind testing. Like you Blumlein 88, you can test that with different filter settings in your DAC, if that functionality in the DAC is there.
Easier and cheaper blind test. Anyone can get a thin lamp cord cheaply, use it as a speaker cable and blind test.If you have balance control on the amplifier, you can have your usual speaker cable connected to one speaker and thin lamp cord to the other speaker.Then ask if you can detect differences between the different channels, and yes I am aware that the placement of the speakers plays a role (when listening to one or the other via the balance control), but you can switch the cables between the speakers a number of times and then see if you can identify which cable is which. But ok, maybe it was too much trouble, uncertainty about the outcome if you do that, maybe it's best to just change the cable set for both speakers and carry out a blind test.

Obviously hidden cable so the listener cannot see which cable goes to which speaker.
OT:
In my opinion, a more fun blind test would be if one person moves (or not) the position of the speakers and then the other listening test person, blindfolded, gets to say if he hears any differences. Sooner or later, depending on how much the speakers are moved and angled, you will hear differences. Real differences, not just imagined.
Then you might also disconnect your biases, preconceived notions about which speaker placement gives the best sound and arrive at a placement that you hadn't thought of before if you do such a blind test.

...then you can move the furniture around and blind test ...but that is perhaps overkill.
