Just got my Hifiberry Dac8x and just wanted to report briefly on noise levels. I have the Dac8x hooked up to my Bryston 3B-SST amp in single-ended mode with a mini-TRS to dual RCA cable. The amp gain is 29 dB. Speakers are Buchardt S400 (about 85 dB sensitivity).
If I put my ear right up to the speaker drivers I can hear a quiet hum. It's inaudible a foot away or so. I don't hear any noise out of my subwoofers (SVS SB-1000 Pro).
In other words, nothing to worry about.
Setup was otherwise very easy, and I have nothing exceptional to report about any sonic differences compared to my Motu M4. (I got this for another project, not to replace the M4).
It may be possible to get a balanced connection -- at the cost of one output channel per balanced connection -- by splitting a signal in camilladsp and inverting one of the outputs, but I don't have the cabling (mini-TRS to XLR) to try this right now.