I believe this applies more to dynamic drivers and not so much to planars.supposedly technically, if I use the 6.3mm output with 32Ω headphones, there will be a change in sound, especially at low frequencies.
BTW, the Topping L30 II recommended earlier is an excellent choice for ultra clean amplification, small foot print, at a great price. I keep one paired to another RME interface I have. I keep its volume full and control my headphone volume through the RME's phone's output level in TotalMix, just like I would if they were plugged in directly - except I have gobs more power.