OK so after some further investigation... Auto power off works when all sources are unplugged, timeout is approx 1 minute.
Heres the issue I found. When plugged into my PC thru USB, and then shutting down the PC, the sample rate briefly unlocks, then immediately reverts to the last-used sample rate. So the D50 still "thinks" it's operational.
Same thing happens when putting the computer to sleep, rather than shutting down. Either way, no data is being sent to the D-50, so I have no idea why it's doing this.
When I manually power ON the D-50 while plugged into the sleeping or shut-down computer, it remains unlocked and shuts off automatically after a minute.
So in the end, under normal use conditions, auto-off only works when I manually unplug the unit. Which kinda defeats the purpose.
Edit: for process of elimination, tried with my wife's MacBook Pro. Sample rate stayed locked during sleep and shutdown, didn't even briefly unlock. I'll try with my work computer later this week, but I really don't think this is the intended behavior.