Threads a bit unbalanced..
No problem - someone grab a Behringer HD400, she'll be alright.
We can still resort to WD-40 and duct tape later...
No ground loops in XLR systems? Nonsense. Mix them with single-ended RCA equipment and the risk is greater. Sorry but this is reality.
Mixing these two disparate worlds does in fact bear lots of potential for grief. One follows a philosophy of "floating with unbalanced connections", the other one adheres to "earthed with balanced connections" instead. "Why do I get interference with <studio monitors> on <PC>?" seems to be one of those FAQs that crop up over and over again with remarkable regularity. A PC is mains earth referenced but has unbalanced I/O, so connecting another IEC Class I device is obviously calling for trouble.
How much trouble you're in will depend upon what you need:
1. Unbalanced source --> balanced input. That's relatively easy. Or at least it would if cable manufacturers could be bothered to get their lazy rear ends off the ground and make some proper adapter cables that actually make
some use of a balanced input instead of being unbalanced all the way. Seriously, I know of
not one pre-made cable that connects signal --> hot and splits unbalanced ground into cold and shield at the unbalanced end. This should mostly work (with some PCB routing related variation), and with an optional ground lift feature, success ratio should be near 100%. Meanwhile, you can also run an unbalanced connection into a line isolator like the trusty HD400 and then continue with balanced cabling - not the cheapest or most ideal option but "plug and play" and working fine in practice.
2. Balanced source --> unbalanced input. That's where it all tends to go haywire. Results will depend upon things like output topology, which in general is not at all transparent to the end user. Those lucky enough to come by a floating output should have few problems assuming the cabling is right (hot --> signal, cold --> ground). With a ground-referenced output you need
another cable (hot --> signal, shield --> ground), and if the device you're connecting to is
not floating, you're pretty much screwed without a line isolator. And then there are the impedance-balanced outputs, which are much the same (except you can short cold and shield with no ill effects) but are occasionally also found on devices that are not mains earth referenced, like little portable mixers - so getting an XLR mic signal into an unbalanced soundcard input won't be an issue at least.
Then there's the issue of level differences. With 12 dB between -10 dBV and +4 dBu, there's the potential for less than ideal matching and reduced dynamic range. Equipment often provides some flexibility but that may not be enough in all cases.
Incidentally, the classic Pin 1 Problem is not entirely dead and seems to crop up on things like less expensive powered monitors quite regularly. (I suspect that some 5-6" KRKs are affected. As is the pre-AES48 Behringer A500.) Running the input connection over a ribbon cable to the main board seems to be easier production wise. Pin 1 could still have a dedicated return from there to star ground, mind you.
These 4.4 mm things... yeah, that's something I could get behind. For some reason I thought they had just 4 segments, not 5 - my bad.
Unfortunately, establishing new connectors in the slow-moving audio world is akin to some modern-day artist / band becoming as big as the Beatles or David Bowie or other vinyl era icons... they can be as good as they want, it still is not likely to happen.