I believe you can do everything if you would use VB-AUDIO MATRIX as system-wide routing center which also provides 64-Ch virtual I/O audio (VAIO) devices to replace your WDM routings.
VB-AUDIO MATRIX redirects any of the digital audio I/O to any of the available ASIO, VASIO, VAIO channels.
I wonder what the additional latency is, as
@dithered talks about a setup for gaming. Those software loopbacks add at least two additional buffers into the chain.
I do not play game with my audio (audio-visual) PCs, but I occasionally view/listen to TV programs, YouTube video clips, DVD movies,
etc. using PANASONIC 55-inch OLED TV TH-55HZ1800 connected to the PC by 10m-long optical HDMI cable, as I shared in detail in
my recent total-system update post #931 on my project thread.
In this TV setup, the 55-inch OLED TV is configured as
second PC monitor of 4K 3840x2160 resolution in refresh rate 60 Hz; all the audio-visual processing, including the TV tuner function, is done within the PC, and only visual video signal is fed into 55-inch OLED TV through optical HDMI cable, whereas all the audio signal goes into system-wide DSP center EKIO via VB-AUDIO MATRIX for
my "ordinary" PC-DSP-based multichannel multi-SP-driver multi-amplifier audio processing/reproduction.
My primary PC monitor for audio(-visual) control is 27-inch LCD screen of 1920x1080 resolution:
Above TV setup is a kind of "reverse-thinking utilization" of 55-inch 4K OLED TV in my audio-visual system, as I intensively described in
my post here #509 (remote thread), and fortunately I have
no lip-sync/latency issue at all, even though two of my completely silent PC in listening room are rather outdated ones;
I dare not install GPU board/card within the PCs (to make/keep them completely silent!), but using the CPU incorporated GPU (iGPU) Intel HD2000 for feeding video signal into primary 27-inch(1920x1080) monitor via DVD-I cable
and into 55-inch 4K(
3840x2160) OLED TV via optical HDMI cable, both in 60 Hz refresh rate.
Furthermore, I have no audible delay/latency issue during the real-time live play of vinyl LP (ref.
#688) by TT DP-57L + AT-PEQ30 (phono preamp) + US-1x2HR (audio interface), as shared
here #692 on my project thread.
Since I do not play (heavy?) games on this setup, sorry but
I do not know the lip-sync/latency issue (or not) in the above setup while gaming.
By the way, in my upstairs office, I also have two of much powerful (but again rather outdated) Intel Xe-CPU PC workstations, one has 8-core 16-thread Xeon ES-2630 v3 CPU and NVIDIA GeForce GTX970 GPU board, the other has 12-core 24-thread Xeon ES-2697 v2 CPU and NVIDIA GeForce GTX TITAN GPU board, for my bio-medical image processing work as well as preparation of diagrams, photos and video clips for ASR Forum; the
dual monitor via DisplayPort are 27-inch EIZO EV2750 monitor (2560 x 1440 pixel) giving 5120 x 1440 pixel desktop area (photo
here).
They are also almost silent PC workstations, and I have desktop audio setup for them with similar 10-Ch DSP processing by EKIO into single DAC to single stereo integrated amplifier driving small 3-way SP plus small sub-woofers. I have never brought them (the Xeon PC workstations) into my audio listening room, however, for testing heavy game play purposes using my main audio system plus 55-inch 4K OLED TV.