It's a studied phenomena. Many speakers experience a bass boost around 160-200Hz from the desktop surface. Here is a study involving 69 speakers and a desktop. The authors derive an generalized notch EQ to deal with the boost caused by the desk.
The notch is based on the median of the responses they measured. Your mileage will vary based on your desk and room. If you can't measure, you can start with a 160Hz notch, -3 or -4 dB, Q=3, and see what helps the most.
As already mentioned, no amp will do this. EQ will.