My room and system setups are the same as those of Gianluca (see attached picture - what's on the left of the left speaker is not a wall but just a column, the room is otherwise open on that side) and I have the same issue, except in my case the image shift is towards the right (2.8 dB of unbalance to be precise). I am 100% sure it's not due to the speakers because I get the same result even if I swap them. In addition, they are active speakers, so amp issues are also ruled out from the equation. Also the DAC and the cables are ruled out, because I have tried swapping the channels at the speakers' input (the cable connectors) and the problem persists. Finally, even the track I am listening cannot be blamed, because I select the MONO mode in my DAC to make sure I am not tricked by the stereo recording (and also because even when in stereo mode, the effect is more or less evident depending by the tracks, but it is clearly there). So nothing remains in the equation except maybe my ears, but If I use phones, or listen to a point source in front of me, or best of all, listen to the second stereo set I have in another room, the image is aways perfectly at the center. The image shift noticed also spontaneously by a friend, without me telling him of its existence. I even swapped the two stereo sets, only to see the problem remain.
So in conclusion It looks obvious that the room and the unhappy positioning of my stereo set are the culprit, but there's an interesting thing to say: no matter how carefully I measure the frequency response of the left and right speaker in my seat position, using a fairly highly accurate measurement setup, the frequency responses of the left and right speaker appear absolutely balanced. On the contrary, when I lower the gain of the right channel by 2.8 dB to center the stereo image and I take a measurement, they appear unbalanced,, obviously with the left about 2.8 dB louder of the right.
My humble conclusion is that sadly, not all the effects of the room and speaker placement can be captured in measurements. More likely, particular ways of measuring the frequency response of the system that can reveal such imbalances may exist, but I am not aware of them.