There is a solid amount of high-quality valve modelling in professional audio tools, from modelling amplifiers (hardware DSP) for guitarists, to modelling plugins etc for guitar amps and effects (LA2A compressors etc). The best ones essentially run something like SPICE in realtime and they have been refined over the last decade to be indistinguishable from the real thing (yes, I've been involved in blind testing). I can imagine this making it into hifi before too long so people can choose it easily if they wish.