Let's put some science behind this. Here is the compression data from Erin's review:
View attachment 509665
With the speakers placed against the wall,
to acheive 80dB with two speakers at 20' from the listening position, each speaker will be outputing around 86.7dB @ 1m considering room gain, boundary reinforcement and speaker separation. We can see in Erin's chart that the LS60 is down about 1dB at 50Hz and 2.5dB at 40Hz. This may or may not be acceptable to the OP. If not, a subwoofer can be added to address the bass rolloff issue.
One issue the subwoofer will not address is dynamics above 3kHz. Most music these days (and I suspect audio for movies, etc.) is compressed, so I don't think it is a significant issue. However, if the OP plans on listening to a fair amount of uncompressed music (e.g., classical music recordings, older recordings, etc.), it will be an issue. How audible it will be I don't know. I have a pair of LS60s, but in a smaller room, and I have not experienced any noticable issues, even when listening to uncompressed music.