umm, yeah... do you know what I did (and still do, to some extent) for a living? I've never seen polypeptides, much less glycoproteins, as a
problem, but rather as an
opportunity.

I am a blood coagulation guy from way back (having started by working, at least a bit, on human fibrinogen glycosylation with R. Reid Townsend a long,
long time ago in his, and my, grad school days). Heck, I worked most of my career with the makers of the first (full length) recombinant human Factor VIII (which was a pretty insane place for a company to start, but start there they (Genetics Institute) did, with Baxter and
Recombinate)... a long time ago now.
EDIT: I see that
Recombinate is - finally - reaching the end of the trail.

I spent a lot of happy hours, and a few unhappy ones, on matters pertaining to it... and a bunch of other coagulation factors, as well, over the years.
But I digress...