So you think all of science is in question then? You do realize that virtually everything that has to do with sensory perception, experience, emotion, behaviour ultimately needs proxy measures to get at and with that there will always be error in measurement and chance. Statistics are not willy-nilly little things, statistics are extremely robust mature mathematical procedures that have been refined and honed by hundreds if not thousands of brilliant mathematicians. They are not perfect, but they are the best thing that we have and I trust them far more than I trust some dude on the Internet who spends a boatload of money on fancy, rarified earth metal cables wrapped in fairy wings and then hears a difference.
I am not sure what level of evidence you will believe in or accept, but thank you, I am good with imperfect science. Far better than the untestable "trust me I can hear it" claims. Beyond that, properly done, blind level matched, multiple trial listening tests when subjected to validated statistical analysis are more than capable of answering these questions whether you or I chose to believe so or not. At one time people believed the world was flat and that the gods determined your fate. Thankfully, in my opinion, science had at those beliefs and sent them scurrying away into the annals of history.
As well, the more we sample the more we diminish the effects of chance in our measurement.