IMO the one to be looking at would be the 4i4 which has a well-performing line-in that is more in the spirit of the 0404's basically measurement-grade input, not to mention a better headphone amp. (It also costs about the same inflation-adjusted.) The front inputs are fine but much like the MOTU M2 with essentially the same THAT 6263 chip, distortion gets a bit so-so towards the treble in particular. Should you be using dynamic microphones, you'd likely appreciate the better EIN when compared to the 0404 though.
It doesn't appear like there's a teardown of a 4th gen Scarlett yet, but about the fanciest opamps I'd be expecting would be the OPA1678s that are gracing newer MOTUs. And probably a 1688 in the headphone amp.
When faced with high(ish) surrounding impedances, about the last thing you want when trying to keep noise down is super-low voltage noise bipolar input opamps. OPA1612s have 1.7 pA/√(Hz) worth of current noise density (which actually is really good for a part that sports 1.1 nV/√(Hz) of voltage noise, but still on the high side absolutely speaking). OPA1642s would be a better bet under these circumstances.