Even though I've read about this stuff (which is new for me) for the past 2 hours, I'm still pretty confused whether I should touch Windows 10 volume sliders/mixer.
I have a Babyface Pro FS, and I recall RME mentioning in their forums that all volume sliders in Windows should always be at 100% when using shared mode/WDM. I understand that with ASIO in DAWs none of this is necessary, but what about using the Babyface with a browser (YouTube, etc) media playback (VLC) and games?
Don't sweat it too much, most of it is inaudbile, plus under the hood there has been progress on Windows. If you want to maximize use of your Babyface just use exclusive mode that bypasses all of windows audip processing and directly sends signal to your babyface, usually even bit perfect.
If you're still nervous, install equalizer APO and when installing its processing on your babyface usb interface, just untick "use original apos". I am not sure what it exactly does, but it eliminates all windows quirks. From this on you can safely use any volume management in windows without fear of climiter or stuff.