I've used the MR4s with a Presonus Sub8 BT which is a similar class to the T5 (8 inch sub), but has a high pass filter so the MR4 don't play below 80 Hz.
By doing this I'm getting Bluetooth connectivity and slightly reduced distortion in the MR4, but I can imagine T5 could also work.
Both MR4 and T5 are class II electrical devices - they don't have a ground plug so you don't need to worry about ground loops so much.
Connect your source to the sub and then your sub's RCS outputs to the MR4's RCA inputs.
On the MR4, use neutral or even reduce bass level on the knob.
You could also get a cheap measurement mic (like Dayton imm-6) to help with subwoofer placement or equalizing the sub if your placement options are limited.
Lastly, if you don't have the MR4 yet, consider the MR3. Through DSP and the new app they have, they allow better finetuning of the crossover between sub and the speakers.