It depends, strongly, on the speaker used, on its complex impedance, how it affects the usual 10uH/1uF output LC filter resonant frequency response at high frequencies. Speakers with prevailing capacitive impedance at highs are worst in this regard. The second amp has to be really load invariant one, like Purifi or linear amp (class A, AB). Even the TPA32XX with PFFB based amps are not load invariant.