The advantage of the coaxial cable is in active speaker systems where each driver is connected to a separate cable. There is no inductive coupling (cross talk) between coaxial cables. Both the electric and magnetic fields due to the signal are confined to the cable. Thus low frequencies from the bass and midrange cannot couple into the tweeter. This is not true if pairs of signal wires (even if they are twisted) are in proximity to one another. With the coax cables you can have a neat cable bundle without having to worry about cross talk. Here is an excerpt from the construction manual for the LX521.4 speakers -
"22) - 25 July 2013 - Speakon connector
Instead of using screw terminal blocks at the speaker end I use a Neutrik 8-pole
Speakon connection. The part numbers in the Mouser catalog are:
568-NL8MPR-BAG male, chassis, Faston tabs, $7.28
568-NL8FC female, cable, screw terminals, $10.44
For a Belden 8-conductor cable 1811A I make the following connections to minimize
crosstalk:
Tweeter: blk-wht
Midrange: brn-blu
Woofer top: grn-red
Woofer bottom: yel-org
Also see FAQ8"