I am experiencing the same issue with my Topping MX3s DAC and a Macbook Pro M1 Pro / 16GB. It's connected via USB to my Dell monitor -> Targus USB Dock -> Macbook. Audio stutters and pops every couple of seconds. A restart sometimes helps but not by much.
The Topping MX3s supports bluetooth and connecting my Macbook to the DAC via bluetooth seemed to resolve the issues for now. I would expect USB connection to be a more stable / clean than bluetooh but seems like this is a widespread issue. From what it sounds like Sonoma also fixes these issues, so hopefully once its ready for production I can revert back to the USB connection.