This device works with cell phones, and is an easy way to add noise cancelling to the basic, stock phone call function. I don't know enough about android or iOS to know if there are ways to use other noise cancelling inside of phone calls, but this is an easy plug and play way to add it if you also have a wired headset. I work in a small, echoey office, and I've tried many different headsets, including ones that advertise that they have passive noise cancellation, and this has worked better (with the Sennheiser PC38X) than anything else at removing extraneous noises. When I'm at home, I can even wash dishes or other chores while on the phone and the person on the other end wouldn't be bothered by the noise, whereas previously my headset picked up too much. While the phone call's audio quality takes a hit, it allows me to use my phone hands-free and more comfortably than before. After having tried many different headsets and getting many different complaints about echoes and other noises, for cellphone calls I've found that adding this dongle to my phone has resulted people telling me that they can hear me with the fewest distractions. It definitely has flaws - the directions are poor, other reviews online said some headsets apparently necessitate an additional adapter, people on both ends think it sounds better when my headset is plugged in directly to my phone (if there aren't echoes), and I don't bother using it on a computer - but in some situations its active noise cancellation does greatly improve the phone call.